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Krishna Reddy Gujjula Industrial and Systems Engineering Curriculum Vitae: KrishnaCV Software: Map2Peak |
Biography
- I am Ph.D. candidate in Department of Industrial and Systems Engineering at Texas A&M University. My dissertation advisor is Dr. Kiavash Kianfar. I have a strong background in mathematical and statistical modeling with application in the field of bioinformatics. My research work includes development of algorithms for analysis of Next Generation Sequencing datasets.
- Before pursuing Ph.D., I received my Bachelor's degree from the Department of Mechanical Engineering at National Institute of Technology, Kurukshetra, India.
Research Interests
- Develop algorithms for ChIP-Seq data analysis.
- Develop faster algorithms to capture Transcription-Factor (TF) binding sites in repeat elements of the genome.
- Develop algorithms to find true alignment for multi-mappable reads.
Publication
- Krishna Reddy Gujjula, Kiavash Kianfar:
Map2Peak: From Unmapped reads to ChIP-Seq Peaks in half the time.
to be submitted to Bioinformatics, in April 2018. - Krishna Reddy Gujjula, Krishnan Ayalur Seshadrinathan, Amirhossein Meisami:
A Hybrid Metaheuristic for the Maximum k-Plex Problem.
Examining Robustness and Vulnerability of Networked Systems 2014: 83-92
Projects
- Intern project: Performed statistical analysis on NGS datasets and developed a real time scalable dashboard to visualize NGS sequencing lab metrics and evaluate lab performance. Dashboard was developed in R-Shiny and was deployed on ThermoFisher server.
- Dissertation project: Developed fast and accurate ChIP-Seq peak calling algorithm to detect transcription factor binding sites. Algorithm has the ability to resolve location of multi-mappable reads and identify binding sites in repeat elements of DNA.
- Gene expression analysis: Developed statistical model for time based differential gene expression analysis to find miR-150 role in negative regulation of B-cell growth.
Teaching
During my time as a graduate student I have acquired extensive experience of teaching both graduate and undergraduate level courses.
- Course Instructor: Economic analysis of engineering projects(ISEN302), Spring and Fall 2017
- Lab Instructor: Statistical Control of Quality(ISEN314), Fall 2016
- Course Instructor: Production Systems Planning(ISEN315), Summer 2015
- Guest Lecturer: Integer Programming(ISEN668), Spring 2017
- Teaching Assistant: Production Systems Planning(ISEN315), Statistical Control of Quality(ISEN314) Fall 2013 to Spring 2015
Awards and Certification
- Graduate Teaching Fellowship, Spring and Fall 2017
- Academy of Future Faculty Certification, Spring 2017
Professional Experience
- Course Instructor: Economic analysis of engineering projects(ISEN302), Spring and Fall 2017
- Summer Intern: R&D Clinical Sequencing Lab, ThermoFisher Scientific, Austin, TX
- Lab Instructor: Statistical Control of Quality(ISEN314), Fall 2016
- Course Instructor: Production Systems Planning(ISEN315), Summer 2015
- Guest Lecturer: Integer Programming(ISEN668), Spring 2017
- Teaching Assistant: Production Systems Planning(ISEN315), Statistical Control of Quality(ISEN314) Fall 2013 to Spring 2015